关键词: 巴马猪, 复杂手术, 复合麻醉, 超长时间, 实验外科

Abstract: Objective Explore a combined anesthesia more than 6 hours for Bama pigs and explore the effectiveness of complicated surgical procedures used in experimental surgery. Method Combining four main medicines: Zoletil, Dexdomitor, Isoflurane, Butorphanol to perform single kidney removal and orthotopic transplantation after renal vein occlusion, deep rectal resection and anastomosis, pancreatic resection + spleen removal + gastric perforation anastomosis. Monitor the vital signs of Bama pigs, as well as sedative, analgesic, and muscle relaxation effects during the entire anesthesia process, and also analysis combined with death cases to evaluate the anesthetic effect of the program. Result 1 Bama pig died of hypovolemic shock, the rest of 12 Bama pigs successfully completed more than 6 hours abdominal surgery, no adverse reactions. Heart rate, blood oxygen saturation, mean arterial pressure, body temperature were stable, and both fluctuate within the normal range. Conclusion This anesthesia program can ensure the anesthesia time of the Bama pig exceed 6 hours, and can successfully complete the operations of abdominal organ removal, blood vessel dissection and anastomosis, tissue cutting and suture by surgical robot. During the operation, the anesthesia is stable, the effect of sedation and analgesia is excellent, pigs wake up quickly post-operation. The four main anesthetics are veterinary drugs, and the storage time is longer after the first use, which fully meets the requirements of experimental surgery for extra-long time and complicated operations.

Key words: Bama pig, complicated operation, combined anesthesia, ultra-long time, experimental surgery